Cameroon’s Littoral region ran a reactive vaccination campaign against cholera February 22-26 in the health districts of Boko, Bonassama, Cité des Palmiers, Deido and Nylon. Targeting 659,758 people ages 1 and older, the campaign represented the fourth phase of a wider multiregional effort aiming at achieving a 95% vaccination rate. Cameroon has been experiencing a cholera outbreak since last October, with six cases recorded since January in the Littoral region. Journal du Cameroun