Uganda’s Karamoja region started its seasonal malaria chemoprevention (SMC) effort on October 26, targeting 270,000 children under age 5 in eight districts (Abim, Amudat, Karenga, Kotido, Moroto, Nabilatuk, Nakapiripit and Napak). SMC will be delivered through a door-to-door approach by community health workers during the high malaria transmission period. Uganda MoH; Malaria Consortium